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Gene Review:

RNF146 - ring finger protein 146

Homo sapiens

Synonyms: DKFZp434O1427, Dactylidin, E3 ubiquitin-protein ligase RNF146, Iduna, RING finger protein 146, ...

von Rotz, R.C. et al.

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Disease relevance of RNF146

However, the up-regulation of dactylidin in highly vulnerable brain tissues of AD patients was confirmed by a quantitative PCR approach, suggesting that dactylidin may function early in the progression of neurodegenerative diseases [1].

Psychiatry related information on RNF146

The novel cytosolic RING finger protein dactylidin is up-regulated in brains of patients with Alzheimer's disease [1].

References

The novel cytosolic RING finger protein dactylidin is up-regulated in brains of patients with Alzheimer's disease. von Rotz, R.C., Kins, S., Hipfel, R., von der Kammer, H., Nitsch, R.M. Eur. J. Neurosci. (2005) [Pubmed]

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