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Gene Review

CYP707A4  -  abscisic acid 8'-hydroxylase 4

Arabidopsis thaliana

Synonyms: cytochrome P450, family 707, polypeptide 4, subfamily A
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High impact information on CYP707A4

  • These candidate genes were functionally expressed in yeast to reveal that members of the CYP707A family, CYP707A1-CYP707A4, encode ABA 8'-hydroxylases [1].

Associations of CYP707A4 with chemical compounds

  • We have previously identified that four members of the Arabidopsis (Arabidopsis thaliana) CYP707A gene family (CYP707A1 to CYP707A4) encode ABA 8'-hydroxylases, and that the cyp707a2 mutants showed an increase in ABA levels in dry and imbibed seeds [2].


  1. The Arabidopsis cytochrome P450 CYP707A encodes ABA 8'-hydroxylases: key enzymes in ABA catabolism. Kushiro, T., Okamoto, M., Nakabayashi, K., Yamagishi, K., Kitamura, S., Asami, T., Hirai, N., Koshiba, T., Kamiya, Y., Nambara, E. EMBO J. (2004) [Pubmed]
  2. CYP707A1 and CYP707A2, which encode abscisic acid 8'-hydroxylases, are indispensable for proper control of seed dormancy and germination in Arabidopsis. Okamoto, M., Kuwahara, A., Seo, M., Kushiro, T., Asami, T., Hirai, N., Kamiya, Y., Koshiba, T., Nambara, E. Plant Physiol. (2006) [Pubmed]
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