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Gene Review

ATCAD4  -  cinnamyl alcohol dehydrogenase 4

Arabidopsis thaliana

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High impact information on CAD4


Associations of CAD4 with chemical compounds

  • The cinnamyl alcohol dehydrogenase (CAD) multigene family in planta encodes proteins catalyzing the reductions of various phenylpropenyl aldehyde derivatives in a substrate versatile manner, and whose metabolic products are the precursors of structural lignins, health-related lignans, and various other metabolites [3].


  1. Functional reclassification of the putative cinnamyl alcohol dehydrogenase multigene family in Arabidopsis. Kim, S.J., Kim, M.R., Bedgar, D.L., Moinuddin, S.G., Cardenas, C.L., Davin, L.B., Kang, C., Lewis, N.G. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  2. Genomic nucleotide sequence of an Arabidopsis thaliana gene encoding a cinnamyl alcohol dehydrogenase. Baucher, M., Van Doorsselaere, J., Gielen, J., Van Montagu, M., Inzé, D., Boerjan, W. Plant Physiol. (1995) [Pubmed]
  3. Crystal structures and catalytic mechanism of the Arabidopsis cinnamyl alcohol dehydrogenases AtCAD5 and AtCAD4. Youn, B., Camacho, R., Moinuddin, S.G., Lee, C., Davin, L.B., Lewis, N.G., Kang, C. Org. Biomol. Chem. (2006) [Pubmed]
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