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Gene Review:

GTE6 - transcription factor GTE6

Arabidopsis thaliana

Synonyms: general transcription factor group E6

Chua, Y.L. et al.

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High impact information on GTE6

GTE6 positively regulates the expression of ASYMMETRIC LEAVES1 (AS1), which encodes a myb-domain protein that controls proximodistal patterning of leaves [1].
The bromodomain protein GTE6 controls leaf development in Arabidopsis by histone acetylation at ASYMMETRIC LEAVES1 [1].
Mutations in GTE6 disrupt the formation of elliptical leaf laminae in mature leaves, whereas overexpression of GTE6 resulted in elongated juvenile leaves [1].

Other interactions of GTE6

Using chromatin immunoprecipitation (ChIP) assays, we show that GTE6 is associated with the promoter and the start of the transcribed region of AS1 and up-regulates expression of AS1 through acetylation of histones H3 and H4 [1].

References

The bromodomain protein GTE6 controls leaf development in Arabidopsis by histone acetylation at ASYMMETRIC LEAVES1. Chua, Y.L., Channelière, S., Mott, E., Gray, J.C. Genes Dev. (2005) [Pubmed]

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