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Gene Review

TGH  -  TATA-box binding protein-interacting...

Arabidopsis thaliana

Synonyms: MYJ24.7, MYJ24_7, TOUGH
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High impact information on TGH

  • Interestingly, we observed a strong genetic interaction between TGH and AMP1 in that tgh-1 amp1-1 double mutants are extremely dwarfed and severely affected in plant development in general and vascular development in particular when compared with the single mutants [1].
  • TGH contains domains with strong similarity to G-patch and SWAP domains, protein domains that are characteristic of RNA binding and processing proteins [1].
  • We initially identified TGH as a yeast two-hybrid system interactor of the transcription initiation factor TATA-box binding protein 2 [1].


  1. The evolutionarily conserved TOUGH protein is required for proper development of Arabidopsis thaliana. Calderon-Villalobos, L.I., Kuhnle, C., Dohmann, E.M., Li, H., Bevan, M., Schwechheimer, C. Plant Cell (2005) [Pubmed]
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