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Gene Review

HCF109  -  protein high chlorophyll fluorescent 109

Arabidopsis thaliana

Synonyms: ATPRFB, MAB16.12, MAB16_12, PEPTIDE RELEASE FACTOR 2, high chlorophyll fluorescent 109
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High impact information on HCF109

  • A point mutation at the last nucleotide of the second intron causes a new splice site farther downstream, resulting in a deletion of seven amino acid residues in the N-terminal region of the Hcf109 protein [1].
  • The high-chlorophyll fluorescence photosynthesis mutant hcf109 of Arabidopsis was characterized in detail to gain insights into the regulatory mechanism of RNA processing in higher plants [2].
  • This result indicates that the trans-regulatory factor encoded by the hcf109 gene is not a general RNA stability factor but that it specifically controls the stability of only these distinct transcripts [2].
  • Because the hcf109 locus was mapped at a distance < 0.1 centimorgans from the phytochrome C gene, its molecular characterization by positional cloning is possible [2].


  1. A peptide chain release factor 2 affects the stability of UGA-containing transcripts in Arabidopsis chloroplasts. Meurer, J., Lezhneva, L., Amann, K., Gödel, M., Bezhani, S., Sherameti, I., Oelmüller, R. Plant Cell (2002) [Pubmed]
  2. A nuclear mutant of Arabidopsis with impaired stability on distinct transcripts of the plastid psbB, psbD/C, ndhH, and ndhC operons. Meurer, J., Berger, A., Westhoff, P. Plant Cell (1996) [Pubmed]
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