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Gene Review

GPR101  -  G protein-coupled receptor 101

Homo sapiens

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High impact information on GPR101


Biological context of GPR101

  • Consistent with this, over-expression of human GPR101 in a yeast-based system yielded an elevated, agonist-independent reporter gene response in the presence of a yeast chimeric Galphas protein [3].


  1. Discovery and mapping of ten novel G protein-coupled receptor genes. Lee, D.K., Nguyen, T., Lynch, K.R., Cheng, R., Vanti, W.B., Arkhitko, O., Lewis, T., Evans, J.F., George, S.R., O'Dowd, B.F. Gene (2001) [Pubmed]
  2. G protein-coupled receptor 101 mRNA expression in the mouse brain: altered expression in the posterior hypothalamus and amygdala by energetic challenges. Nilaweera, K.N., Ozanne, D., Wilson, D., Mercer, J.G., Morgan, P.J., Barrett, P. J. Neuroendocrinol. (2007) [Pubmed]
  3. Characterization of Gpr101 expression and G-protein coupling selectivity. Bates, B., Zhang, L., Nawoschik, S., Kodangattil, S., Tseng, E., Kopsco, D., Kramer, A., Shan, Q., Taylor, N., Johnson, J., Sun, Y., Chen, H.M., Blatcher, M., Paulsen, J.E., Pausch, M.H. Brain Res. (2006) [Pubmed]
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