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Gene Review

ARF6  -  auxin response factor 6

Arabidopsis thaliana

Synonyms: T4K22.6, T4K22_6
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High impact information on ARF6

  • Wild-type pollen grew poorly in arf6 arf8 gynoecia, correlating with ARF6 and ARF8 expression in style and transmitting tract [1].
  • ARF6 and ARF8 transcripts are cleavage targets of the microRNA miR167, and overexpressing miR167 mimicked arf6 arf8 phenotypes [1].
  • Auxin response factors ARF6 and ARF8 promote jasmonic acid production and flower maturation [2].

Biological context of ARF6

  • The transgenic phenotypes suggest that miR167 may repress ARF6 at the level of translation [3].

Associations of ARF6 with chemical compounds


Other interactions of ARF6

  • Mutations in the miR167 target sites of ARF6 or ARF8 caused ectopic expression of these genes in domains of both ovules and anthers where miR167 was normally present [1].


  1. Arabidopsis microRNA167 controls patterns of ARF6 and ARF8 expression, and regulates both female and male reproduction. Wu, M.F., Tian, Q., Reed, J.W. Development (2006) [Pubmed]
  2. Auxin response factors ARF6 and ARF8 promote jasmonic acid production and flower maturation. Nagpal, P., Ellis, C.M., Weber, H., Ploense, S.E., Barkawi, L.S., Guilfoyle, T.J., Hagen, G., Alonso, J.M., Cohen, J.D., Farmer, E.E., Ecker, J.R., Reed, J.W. Development (2005) [Pubmed]
  3. Plant fertility defects induced by the enhanced expression of microRNA167. Ru, P., Xu, L., Ma, H., Huang, H. Cell Res. (2006) [Pubmed]
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