The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

TOM2A  -  tobamovirus multiplication 2A protein

Arabidopsis thaliana

Synonyms: F5D14.17, F5D14_17, tobamovirus multiplication 2A
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of TOM2A

  • The data presented here suggest that TOM2A is also an integral part of the tobamovirus replication complex [1].
 

High impact information on TOM2A

  • The split-ubiquitin assay demonstrated an interaction of TOM2A both with itself and with TOM1, an integral membrane protein of A.thaliana presumed to be an essential constituent of tobamovirus replication complex [1].
  • TOM2A encodes a 280 amino acid putative four-pass transmembrane protein with a C-terminal farnesylation signal, while TOM2B encodes a 122 amino acid basic protein [1].
 

Anatomical context of TOM2A

  • These observations suggest that the formation of tobamoviral RNA replication complex occurs on TOM1-containing membranes and is facilitated by TOM2A [2].

References

  1. Arabidopsis TOBAMOVIRUS MULTIPLICATION (TOM) 2 locus encodes a transmembrane protein that interacts with TOM1. Tsujimoto, Y., Numaga, T., Ohshima, K., Yano, M.A., Ohsawa, R., Goto, D.B., Naito, S., Ishikawa, M. EMBO J. (2003) [Pubmed]
  2. Subcellular localization of host and viral proteins associated with tobamovirus RNA replication. Hagiwara, Y., Komoda, K., Yamanaka, T., Tamai, A., Meshi, T., Funada, R., Tsuchiya, T., Naito, S., Ishikawa, M. EMBO J. (2003) [Pubmed]
 
WikiGenes - Universities