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Gene Review

EMILIN2  -  elastin microfibril interfacer 2

Homo sapiens

Synonyms: EMILIN-2, Elastin microfibril interface-located protein 2, Elastin microfibril interfacer 2, FLJ33200, FOAP-10, ...
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High impact information on EMILIN2

  • The mRNA expression of EMILIN-2 is more restricted compared with that of EMILIN-1; highest levels are present in fetal heart and adult lung, whereas, differently from EMILIN-1, adult aorta, small intestine, and appendix show very low expression, and adult uterus and fetal kidney are negative [1].
  • No reporter gene activity was detected when EMI-1 was co-transformed with the C-terminal gC1q-1 domain excluding a head-to-tail multimerization; conversely, a strong interaction was detected when the EMI-1 domain was co-transformed with the gC1q-2 domain of EMILIN-2 [2].

Other interactions of EMILIN2

  • Isolation and characterization of EMILIN-2, a new component of the growing EMILINs family and a member of the EMI domain-containing superfamily [1].


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