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MeSH Review

Fetal Heart

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Disease relevance of Fetal Heart


High impact information on Fetal Heart

  • Direct cocaine administration to the fetus produced smaller increases in fetal heart rate and blood pressure than those observed following maternal cocaine injection, and no significant changes in fetal arterial blood gas values [6].
  • Testing rates for 24-hour urinary estriol levels (EST), diagnostic ultrasound, and antepartum fetal heart rate testing (AFHRT) were examined in 8,527 deliveries from 1975 through 1978 [7].
  • In contrast, cyclin A mRNA was undetectable in adult hearts whereas cyclin A mRNA and protein were readily detectable in fetal hearts and cardiomyocytes, respectively [8].
  • Cyclin B mRNA was detectable in adult hearts, although at a level markedly lower than that in fetal hearts [8].
  • Responsiveness to glucagon in fetal hearts. Species variability and apparent disparities between changes in beating, adenylate cyclase activation, and cyclic AMP concentration [9].

Chemical compound and disease context of Fetal Heart


Biological context of Fetal Heart


Anatomical context of Fetal Heart


Associations of Fetal Heart with chemical compounds


Gene context of Fetal Heart


Analytical, diagnostic and therapeutic context of Fetal Heart


  1. Characterization of troponin T dilated cardiomyopathy mutations in the fetal troponin isoform. Venkatraman, G., Gomes, A.V., Kerrick, W.G., Potter, J.D. J. Biol. Chem. (2005) [Pubmed]
  2. Prediction and therapy of intrauterine and late-onset neonatal hyperthyroidism. Zakarija, M., McKenzie, J.M., Hoffman, W.H. J. Clin. Endocrinol. Metab. (1986) [Pubmed]
  3. Regulation of gene expression in the endocrine heart. Durocher, D., Grépin, C., Nemer, M. Recent Prog. Horm. Res. (1998) [Pubmed]
  4. Effects of magnesium sulfate on the fetal heart rate response during acute hypoxemia in goats. Sameshima, H., Ikenoue, T., Kamitomo, M., Sakamoto, H. J. Soc. Gynecol. Investig. (1996) [Pubmed]
  5. Role of vasopressin in mediation of fetal cardiovascular responses to acute hypoxia. Piacquadio, K.M., Brace, R.A., Cheung, C.Y. Am. J. Obstet. Gynecol. (1990) [Pubmed]
  6. Effect of cocaine on uterine blood flow and fetal oxygenation. Woods, J.R., Plessinger, M.A., Clark, K.E. JAMA (1987) [Pubmed]
  7. Variation in antenatal testing over time and between clinic settings. Read, J.L., Stern, R.S., Thibodeau, L.A., Geer, D.E., Klapholz, H. JAMA (1983) [Pubmed]
  8. Disappearance of cyclin A correlates with permanent withdrawal of cardiomyocytes from the cell cycle in human and rat hearts. Yoshizumi, M., Lee, W.S., Hsieh, C.M., Tsai, J.C., Li, J., Perrella, M.A., Patterson, C., Endege, W.O., Schlegel, R., Lee, M.E. J. Clin. Invest. (1995) [Pubmed]
  9. Responsiveness to glucagon in fetal hearts. Species variability and apparent disparities between changes in beating, adenylate cyclase activation, and cyclic AMP concentration. Wildenthal, K., Allen, D.O., Karlsson, J., Wakeland, J.R., Clark, C.M. J. Clin. Invest. (1976) [Pubmed]
  10. Atrial and ventricular fetal heart rate patterns in isolated congenital complete heart block detected by magnetocardiography. Wakai, R.T., Leuthold, A.C., Martin, C.B. Am. J. Obstet. Gynecol. (1998) [Pubmed]
  11. Effects of intracervical prostaglandin E2 on fetal heart rate and uterine activity patterns in the presence of oligohydramnios. Larson, J.D., Rayburn, W.F., Turnbull, G.L., Schwartz, W.J., Stanley, J.R., Christensen, H.D. Am. J. Obstet. Gynecol. (1995) [Pubmed]
  12. Acid-base characteristics of fetuses with intrauterine growth retardation during labor and delivery. Lin, C.C., Moawad, A.H., Rosenow, P.J., River, P. Am. J. Obstet. Gynecol. (1980) [Pubmed]
  13. A study on intrauterine fetal resuscitation with terbutaline. Patriarco, M.S., Viechnicki, B.M., Hutchinson, T.A., Klasko, S.K., Yeh, S.Y. Am. J. Obstet. Gynecol. (1987) [Pubmed]
  14. Human basic fibroblast growth factor: nucleotide sequence and genomic organization. Abraham, J.A., Whang, J.L., Tumolo, A., Mergia, A., Friedman, J., Gospodarowicz, D., Fiddes, J.C. EMBO J. (1986) [Pubmed]
  15. Cis-acting sequences that modulate atrial natriuretic factor gene expression. Seidman, C.E., Wong, D.W., Jarcho, J.A., Bloch, K.D., Seidman, J.G. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  16. Thyroid hormone regulates expression of a transfected alpha-myosin heavy-chain fusion gene in fetal heart cells. Gustafson, T.A., Markham, B.E., Bahl, J.J., Morkin, E. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  17. Effect of caffeine on expression of cardiac myosin heavy chain gene in adult hypothyroid and fetal rats. Imamura, S., Kimura, M., Hiratsuka, E., Takao, A., Matsuoka, R. Circ. Res. (1992) [Pubmed]
  18. Short-term (0-48 h) effects of maternal betamethasone administration on fetal heart rate and its variability. Lunshof, M.S., Boer, K., Wolf, H., Koppen, S., Velderman, J.K., Mulder, E.J. Pediatr. Res. (2005) [Pubmed]
  19. The human heart beta-adrenergic receptors. II. Coupling of beta 2-adrenergic receptors with the adenylate cyclase system. Waelbroeck, M., Taton, G., Delhaye, M., Chatelain, P., Camus, J.C., Pochet, R., Leclerc, J.L., De Smet, J.M., Robberecht, P., Christophe, J. Mol. Pharmacol. (1983) [Pubmed]
  20. Afferent and efferent components of the cardiovascular reflex responses to acute hypoxia in term fetal sheep. Giussani, D.A., Spencer, J.A., Moore, P.J., Bennet, L., Hanson, M.A. J. Physiol. (Lond.) (1993) [Pubmed]
  21. Distinct alpha 7A beta 1 and alpha 7B beta 1 integrin expression patterns during mouse development: alpha 7A is restricted to skeletal muscle but alpha 7B is expressed in striated muscle, vasculature, and nervous system. Velling, T., Collo, G., Sorokin, L., Durbeej, M., Zhang, H., Gullberg, D. Dev. Dyn. (1996) [Pubmed]
  22. A differential effect of thyroxine and glucocorticoids on fetal brain and heart insulin receptor. Devaskar, S.U., Grim, P.F., Devaskar, U.P. Pediatr. Res. (1985) [Pubmed]
  23. Expression of multiple gap junction proteins in human fetal and infant hearts. Chen, S.C., Davis, L.M., Westphale, E.M., Beyer, E.C., Saffitz, J.E. Pediatr. Res. (1994) [Pubmed]
  24. Effects of thyrotropin-releasing hormone on fetal heart rate. Gyselaers, W., Spitz, B., de Zegher, F., Van Ballaer, P., Hanssens, M., Van Assche, F.A. Lancet (1992) [Pubmed]
  25. Oxytocin in cardiac ontogeny. Jankowski, M., Danalache, B., Wang, D., Bhat, P., Hajjar, F., Marcinkiewicz, M., Paquin, J., McCann, S.M., Gutkowska, J. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  26. Hey basic helix-loop-helix transcription factors are repressors of GATA4 and GATA6 and restrict expression of the GATA target gene ANF in fetal hearts. Fischer, A., Klattig, J., Kneitz, B., Diez, H., Maier, M., Holtmann, B., Englert, C., Gessler, M. Mol. Cell. Biol. (2005) [Pubmed]
  27. Cardiac troponin T isoforms affect the Ca(2+) sensitivity of force development in the presence of slow skeletal troponin I: insights into the role of troponin T isoforms in the fetal heart. Gomes, A.V., Venkatraman, G., Davis, J.P., Tikunova, S.B., Engel, P., Solaro, R.J., Potter, J.D. J. Biol. Chem. (2004) [Pubmed]
  28. Regulation of adult and fetal myocardial phosphofructokinase. Relief of cooperativity and competition between fructose 2,6-bisphosphate, ATP, and citrate. Bristow, J., Bier, D.M., Lange, L.G. J. Biol. Chem. (1987) [Pubmed]
  29. Steroidogenic enzyme gene expression in the human heart. Kayes-Wandover, K.M., White, P.C. J. Clin. Endocrinol. Metab. (2000) [Pubmed]
  30. Human protein tyrosine phosphatase-like gene: expression profile, genomic structure, and mutation analysis in families with ARVD. Li, D., Gonzalez, O., Bachinski, L.L., Roberts, R. Gene (2000) [Pubmed]
  31. Expression of proliferating cell markers in normal and diseased human hearts. Arbustini, E., Diegoli, M., Grasso, M., Fasani, R., D'Armini, A., Martinelli, L., Goggi, C., Campana, C., Gavazzi, A., Viganò, M. Am. J. Cardiol. (1993) [Pubmed]
  32. Analysis of mRNA expression and cloning of a novel plasma membrane Ca(2+)-ATPase splice variant in human heart. Santiago-García, J., Mas-Oliva, J., Saavedra, D., Zarain-Herzberg, A. Mol. Cell. Biochem. (1996) [Pubmed]
  33. Comparative genomics on DKK2 and DKK4 orthologs. Katoh, Y., Katoh, M. Int. J. Mol. Med. (2005) [Pubmed]
  34. Identification of differentially expressed genes in rat aortic allograft vasculopathy. Chen, J., Myllärniemi, M., Akyürek, L.M., Häyry, P., Marsden, P.A., Paul, L.C. Am. J. Pathol. (1996) [Pubmed]
  35. hKChIP2 is a functional modifier of hKv4.3 potassium channels: cloning and expression of a short hKChIP2 splice variant. Decher, N., Uyguner, O., Scherer, C.R., Karaman, B., Yüksel-Apak, M., Busch, A.E., Steinmeyer, K., Wollnik, B. Cardiovasc. Res. (2001) [Pubmed]
  36. The incidence of fetal heart rate changes after intrathecal fentanyl labor analgesia. Palmer, C.M., Maciulla, J.E., Cork, R.C., Nogami, W.M., Gossler, K., Alves, D. Anesth. Analg. (1999) [Pubmed]
  37. The effects of bupivacaine and chloroprocaine as local anesthetics for epidural anesthesia of fetal heart rate monitoring parameters. Lavin, J.P., Samuels, S.V., Miodovnik, M., Holroyde, J., Loon, M., Joyce, T. Am. J. Obstet. Gynecol. (1981) [Pubmed]
  38. Lumbar epidural analgesia with bupivacaine in labor. Determination of drug concentration and pH in fetal scalp blood, and continuous fetal heart rate monitoring. Belfrage, P., Raabe, N., Thalme, B., Berlin, A. Am. J. Obstet. Gynecol. (1975) [Pubmed]
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