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Gene Review:

SPA4 - SPA1-related 4 protein

Arabidopsis thaliana

Synonyms: F8L10.5, F8L10_5, SPA1-related 4

Oravecz, A. et al., Fittinghoff, K. et al., Laubinger, S. et al., Laubinger, S. et al.

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High impact information on SPA4

SUPPRESSOR OF PHYTOCHROME A-105 family proteins (SPA1 to SPA4) that are required for COP1 function in dark and visible light are not essential in the response to UV-B [1].
Mutations in SPA1 cause phyA-independent early flowering under short day (SD) but not long day (LD) conditions, and this phenotype is enhanced by additional loss of SPA3 and SPA4 function [2].
Levels of SPA1, SPA3 and SPA4 transcript are increased by red, far-red and blue light, consistent with a role of these three SPA genes in light-grown seedlings [3].

Biological context of SPA4

Taken together, the analysis of SPA transcript levels suggests that differences in SPA gene expression patterns contribute to divergence in SPA1-SPA4 function [3].

Other interactions of SPA4

Here, we investigate the functions of SPA3 and SPA4, two very closely related genes coding for proteins with 74% identical amino acids [4].

References

CONSTITUTIVELY PHOTOMORPHOGENIC1 is required for the UV-B response in Arabidopsis. Oravecz, A., Baumann, A., Máté, Z., Brzezinska, A., Molinier, J., Oakeley, E.J., Adám, E., Schäfer, E., Nagy, F., Ulm, R. Plant Cell (2006) [Pubmed]
Arabidopsis SPA proteins regulate photoperiodic flowering and interact with the floral inducer CONSTANS to regulate its stability. Laubinger, S., Marchal, V., Gentilhomme, J., Wenkel, S., Adrian, J., Jang, S., Kulajta, C., Braun, H., Coupland, G., Hoecker, U. Development (2006) [Pubmed]
Functional and expression analysis of Arabidopsis SPA genes during seedling photomorphogenesis and adult growth. Fittinghoff, K., Laubinger, S., Nixdorf, M., Fackendahl, P., Baumgardt, R.L., Batschauer, A., Hoecker, U. Plant J. (2006) [Pubmed]
The SPA1-like proteins SPA3 and SPA4 repress photomorphogenesis in the light. Laubinger, S., Hoecker, U. Plant J. (2003) [Pubmed]

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