The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

TRAF7  -  TNF receptor-associated factor 7, E3...

Homo sapiens

Synonyms: DKFZp586I021, E3 ubiquitin-protein ligase TRAF7, MGC7807, RFWD1, RING finger and WD repeat-containing protein 1, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on TRAF7

  • CYLD in turn leads to the inhibition of TRAF6 and TRAF7 likely via a deubiquitination-dependent mechanism [1].
  • Depletion of TRAF7 by antisense RNA inhibited MEKK3-mediated AP1 and CHOP activation [2].
  • Moreover, overexpression of TRAF7 induced caspase-dependent apoptosis [2].
  • In this report, we identified a protein designated as TRAF7, which contains a RING finger domain and a zinc finger domain that are mostly conserved with those of TRAFs [2].
  • Additional analysis showed expansion of the deletion affecting the adjacent downstream-located genes RAB26 and TRAF7, as well as the great majority of CASKIN1 [3].


WikiGenes - Universities