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Gene Review:

RAB26 - RAB26, member RAS oncogene family

Homo sapiens

Synonyms: Ras-related protein Rab-26

Yoshie, S. et al., Seki, N. et al.

Yoshie, Imai, Nashida, Shimomura,

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High impact information on RAB26

Supporting this, the immunocytochemical reaction for Rab26 was localized immediately around secretory granules in the acinar cells [1].
Expression, characterization, and localization of Rab26, a low molecular weight GTP-binding protein, in the rat parotid gland [1].
cDNA cloning of a human RAB26-related gene encoding a Ras-like GTP-binding protein on chromosome 16p13.3 region [2].
The RAB26-related gene consists of eight exons that span about 44kb of the genome DNA [2].

Analytical, diagnostic and therapeutic context of RAB26

Reverse transcription-coupled polymerase chain reaction (RT-PCR) demonstrated that the RAB26-related messenger RNA was predominantly expressed in adult and fetal brain [2].
Western blotting using an antibody against the Rab26-specific, C-terminal peptide detected the His-tagged Rab26 protein as a single 27-kDa band [1].
We further examined the characteristics and localization of Rab26 by western blotting and light and electron microscopic immunocytochemistry [1].

References

Expression, characterization, and localization of Rab26, a low molecular weight GTP-binding protein, in the rat parotid gland. Yoshie, S., Imai, A., Nashida, T., Shimomura, H. Histochem. Cell Biol. (2000) [Pubmed]
cDNA cloning of a human RAB26-related gene encoding a Ras-like GTP-binding protein on chromosome 16p13.3 region. Seki, N., Yoshikawa, T., Hattori, A., Miyajima, N., Muramatsu, M., Saito, T. J. Hum. Genet. (2000) [Pubmed]

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