Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

PRADC1 - protease-associated domain containing 1

Homo sapiens

Synonyms: C2orf7, MGC13004, PAP21, Protease-associated domain-containing protein 1, Protease-associated domain-containing protein of 21 kDa, ...

Zhou, Y.B. et al.

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High impact information on C2orf7

Western blotting assay indicated that the c-Myc tagged hPAP21 could be secreted into culture medium in the transfected Chinese hamster ovary cells [1].
To define whether the glycosylation was important process for its secretion, endoglycosidase H (Endo H) and PNGase F (PNG F) were employed to evaluate the effect of glycosylation types on secretion of hPAP21 [1].
N-glycosylation is required for efficient secretion of a novel human secreted glycoprotein, hPAP21 [1].

References

N-glycosylation is required for efficient secretion of a novel human secreted glycoprotein, hPAP21. Zhou, Y.B., Liu, F., Zhu, Z.D., Zhu, H., Zhang, X., Wang, Z.Q., Liu, J.H., Han, Z.G. FEBS Lett. (2004) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

PRADC1	Bos taurus
PRADC1	Canis lupus familiaris
CG9849	Drosophila melanogaster
PRADC1	Gallus gallus
PRADC1	Macaca mulatta
Pradc1	Mus musculus
PRADC1	Pan troglodytes
Pradc1	Rattus norvegicus
pradc1	Xenopus (Silurana) tropicalis

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