Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

EFS - histone-lysine N-methyltransferase ASHH2

Arabidopsis thaliana

Synonyms: ASH1 HOMOLOG 2, ASHH2, CAROTENOID CHLOROPLAST REGULATORY1, CCR1, EARLY FLOWERING IN SHORT DAYS, ...

Kim, S.Y. et al., Kim, S.Y. et al.

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High impact information on EFS

Lesions in this methyl transferase, EARLY FLOWERING IN SHORT DAYS (EFS), result in reduced levels of histone H3 Lys 4 trimethylation in FLC chromatin [1].
This increase in trimethylation requires a PAF1-like complex and EARLY FLOWERING IN SHORT DAYS (EFS), a putative histone H3 methyltransferase [2].

References

Establishment of the vernalization-responsive, winter-annual habit in Arabidopsis requires a putative histone H3 methyl transferase. Kim, S.Y., He, Y., Jacob, Y., Noh, Y.S., Michaels, S., Amasino, R. Plant Cell (2005) [Pubmed]
SUPPRESSOR OF FRI 4 encodes a nuclear-localized protein that is required for delayed flowering in winter-annual Arabidopsis. Kim, S.Y., Michaels, S.D. Development (2006) [Pubmed]

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