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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

PAF1  -  proteasome alpha subunit F1

Arabidopsis thaliana

Synonyms: 20S PROTEASOME SUBUNIT PAF1, ARS5, ARSENIC TOLERANCE 5, ATPSM30, MJB21.17, ...
 
 
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High impact information on PAF1

  • These data are consistent with a model in which SUF4 may act to specifically recruit EFS and the PAF1-like complex to the FLC locus [1].
  • Southern blot analysis indicates that the Arabidopsis genome contains numerous sequences closely related to AtPSM30, consistent with recent reports of at least two other proteasome genes in Arabidopsis [2].
 

Biological context of PAF1

  • An interesting distinction between the phenotypes of suf4 mutants and mutants in efs or the PAF1-like complex is observed in the expression of genes that are adjacent to FLC or FLC-like genes [1].
 

Other interactions of PAF1

  • As with mutants in efs or the PAF1-like complex, suf4 mutants show reduced H3K4 trimethylation at FLC [1].

References

  1. SUPPRESSOR OF FRI 4 encodes a nuclear-localized protein that is required for delayed flowering in winter-annual Arabidopsis. Kim, S.Y., Michaels, S.D. Development (2006) [Pubmed]
  2. An Arabidopsis gene homologous to mammalian and insect genes encoding the largest proteasome subunit. Shirley, B.W., Goodman, H.M. Mol. Gen. Genet. (1993) [Pubmed]
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