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Gene Review

LUP2  -  lupeol synthase 2

Arabidopsis thaliana

Synonyms: ATLUP2, YUP8H12R.43, YUP8H12R_43
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High impact information on ATLUP2

  • ATLUPI and ATLUP2 are representative of a small subfamily (A) of at least five genes, whereas ATPEN1 is representative of a subfamily (B) of at least seven genes [1].
  • ATLUP2 is therefore a typical multifunctional enzyme [1].
  • Whereas ATLUP1 is essentially involved in the synthesis of lupeol, ATLUP2 catalyses the production of lupeol, beta- and alpha-amyrin (in a 15:55:30 ratio) [1].


  1. Molecular cloning and expression in yeast of 2,3-oxidosqualene-triterpenoid cyclases from Arabidopsis thaliana. Husselstein-Muller, T., Schaller, H., Benveniste, P. Plant Mol. Biol. (2001) [Pubmed]
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