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Chemical Compound Review

Viminalol     (3S,4aR,6aR,6bS,8aR,11R,12S,12 aR,14aR...

Synonyms: a-amyrin, alpha-Amyrin, alpha-Amyrine, alpha-Amyrenol, CHEMBL455357, ...
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High impact information on alpha-Amyrine


Biological context of alpha-Amyrine


Anatomical context of alpha-Amyrine

  • When administered orally at 66 mg/kg BW every 48 h for 5 days from days 32 to 40 post-adjuvant and assessed on day 50, alpha-amyrin palmitate returned the increases in serum hyaluronate and blood granulocytes toward non-arthritic levels and corrected the moderate anaemia of adjuvant arthritis [8].

Associations of alpha-Amyrine with other chemical compounds


Gene context of alpha-Amyrine

  • Olean-12-enol (16), isomultiflorenol (8), and lupeol (23) were the dominant alcohols in the Cucurbitaceae family, whereas alpha-amyrin (urs-12-enol) (20) was the dominant triterpene alcohol in ATF and MNT [11].

Analytical, diagnostic and therapeutic context of alpha-Amyrine


  1. Molecular cloning and expression in yeast of 2,3-oxidosqualene-triterpenoid cyclases from Arabidopsis thaliana. Husselstein-Muller, T., Schaller, H., Benveniste, P. Plant Mol. Biol. (2001) [Pubmed]
  2. Chemical study of triterpenoid resinous materials in archaeological findings by means of direct exposure electron ionisation mass spectrometry and gas chromatography/mass spectrometry. Modugno, F., Ribechini, E., Colombini, M.P. Rapid Commun. Mass Spectrom. (2006) [Pubmed]
  3. Topical antiinflammatory effects of the ether extract from Protium kleinii and alpha-amyrin pentacyclic triterpene. Otuki, M.F., Vieira-Lima, F., Malheiros, A., Yunes, R.A., Calixto, J.B. Eur. J. Pharmacol. (2005) [Pubmed]
  4. Lipoxygenase inhibition by anadanthoflavone, a new flavonoid from the aerial parts of Anadenanthera colubrina. Gutierrez-Lugo, M.T., Deschamps, J.D., Holman, T.R., Suarez, E., Timmermann, B.N. Planta Med. (2004) [Pubmed]
  5. Eudesmanolides and Other Constituents from Artemisia argyi. Tan, R., Jia, Z. Planta Med. (1992) [Pubmed]
  6. Molecular cloning and functional expression of a multifunctional triterpene synthase cDNA from a mangrove species Kandelia candel (L.) Druce. Basyuni, M., Oku, H., Inafuku, M., Baba, S., Iwasaki, H., Oshiro, K., Okabe, T., Shibuya, M., Ebizuka, Y. Phytochemistry (2006) [Pubmed]
  7. Isoprene derivatives from the leaves and callus cultures of Vaccinium corymbosum var. bluecrop. Migas, P., Cisowski, W., Dembińska-Migas, W. Acta poloniae pharmaceutica. (2005) [Pubmed]
  8. Effect of alpha-amyrin palmitate on adjuvant arthritis. Kweifio-Okai, G., Bird, D., Eu, P., Carroll, A.R., Ambrose, R., Field, B. Drugs under experimental and clinical research. (1994) [Pubmed]
  9. Herbal remedies of the Maritime Indians: sterols and triterpenes of Achillea millefolium L. (Yarrow). Chandler, R.F., Hooper, S.N., Hooper, D.L., Jamieson, W.D., Flinn, C.G., Safe, L.M. Journal of pharmaceutical sciences. (1982) [Pubmed]
  10. Phytochemical and pharmacological studies on Sideritis taurica Stephan ex Wild. Aboutabl, E.A., Nassar, M.I., Elsakhawy, F.M., Maklad, Y.A., Osman, A.F., El-Khrisy, E.A. Journal of ethnopharmacology. (2002) [Pubmed]
  11. Unsaponifiable lipid constituents of some underutilized tropical seed oils. Esuoso, K.O., Lutz, H., Bayer, E., Kutubuddin, M. J. Agric. Food Chem. (2000) [Pubmed]
  12. Molecular cloning and functional expression of triterpene synthases from pea (Pisum sativum) new alpha-amyrin-producing enzyme is a multifunctional triterpene synthase. Morita, M., Shibuya, M., Kushiro, T., Masuda, K., Ebizuka, Y. Eur. J. Biochem. (2000) [Pubmed]
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