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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

PIGY  -  phosphatidylinositol glycan anchor...

Homo sapiens

Synonyms: MGC14156, PIG-Y, Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y, Phosphatidylinositol-glycan biosynthesis class Y protein
 
 
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Disease relevance of PIGY

 

High impact information on PIGY

  • In addition to the potential coding sequence downstream of the gag-pol region, PIGY has a primer binding site complementary to tRNA(asp) and a polypurine tract with a TGGGG motif and is of large size (13,645 bp) [2].
  • PIGY is present in the pea genome in 1-5x10(3) copies and is transcriptionally active, suggesting that some of these elements may still be capable of active transposition [2].
  • One distinctive feature of PIGY is that its env-like region is actually composed of two similar ORFs, each of which encodes a protein with similarity to the Athila envelope-like protein [2].

References

  1. The initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-Y, a seventh component. Murakami, Y., Siripanyaphinyo, U., Hong, Y., Tashima, Y., Maeda, Y., Kinoshita, T. Mol. Biol. Cell (2005) [Pubmed]
  2. PIGY, a new plant envelope-class LTR retrotransposon. Neumann, P., Pozárková, D., Koblízková, A., Macas, J. Mol. Genet. Genomics (2005) [Pubmed]
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