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Gene Review

SUP6  -  tRNA

Saccharomyces cerevisiae S288c

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Disease relevance of SUP6

  • Although the SUP6 delta fragment is contained within a 750-bp restriction fragment, isolated from Saccharomyces cerevisiae, and contains no encoded CCA, the primary transcript, which originates from an E. coli promoter, approx. 1000 bp upstream, is processed to a mature, functional transfer RNA [1].

High impact information on SUP6


Chemical compound and disease context of SUP6


Biological context of SUP6


  1. Functional expression of a yeast ochre suppressor tRNA gene in Escherichia coli. Rossi, J.J., Schold, M., Larson, G.P., Wallace, R.B. Gene (1982) [Pubmed]
  2. The yeast tRNATyr gene intron is essential for correct modification of its tRNA product. Johnson, P.F., Abelson, J. Nature (1983) [Pubmed]
  3. Intron-dependent formation of pseudouridines in the anticodon of Saccharomyces cerevisiae minor tRNA(Ile). Szweykowska-Kulinska, Z., Senger, B., Keith, G., Fasiolo, F., Grosjean, H. EMBO J. (1994) [Pubmed]
  4. A yeast tRNA precursor containing a pre-mRNA intron is spliced via the pre-mRNA splicing mechanism. Köhrer, K., Vogel, K., Domdey, H. EMBO J. (1990) [Pubmed]
  5. Tagetitoxin inhibition of RNA polymerase III transcription results from enhanced pausing at discrete sites and is template-dependent. Steinberg, T.H., Burgess, R.R. J. Biol. Chem. (1992) [Pubmed]
  6. Gene conversion and intragenic recombination at the SUP6 locus and the surrounding region in Saccharomyces cerevisiae. Dicarprio, L., Hastings, P.J. Genetics (1976) [Pubmed]
  7. Fifteen open reading frames in a 30.8 kb region of the right arm of chromosome VI from Saccharomyces cerevisiae. Eki, T., Naitou, M., Hagiwara, H., Abe, M., Ozawa, M., Sasanuma, S., Sasanuma, M., Tsuchiya, Y., Shibata, T., Watanabe, K. Yeast (1996) [Pubmed]
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