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Genes, Suppressor

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Gene context of Genes, Suppressor


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  2. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Liaw, D., Marsh, D.J., Li, J., Dahia, P.L., Wang, S.I., Zheng, Z., Bose, S., Call, K.M., Tsou, H.C., Peacocke, M., Eng, C., Parsons, R. Nat. Genet. (1997) [Pubmed]
  3. A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice. Nicol, C.J., Harrison, M.L., Laposa, R.R., Gimelshtein, I.L., Wells, P.G. Nat. Genet. (1995) [Pubmed]
  4. Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL. Hon, W.C., Wilson, M.I., Harlos, K., Claridge, T.D., Schofield, C.J., Pugh, C.W., Maxwell, P.H., Ratcliffe, P.J., Stuart, D.I., Jones, E.Y. Nature (2002) [Pubmed]
  5. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Hahn, S.A., Schutte, M., Hoque, A.T., Moskaluk, C.A., da Costa, L.T., Rozenblum, E., Weinstein, C.L., Fischer, A., Yeo, C.J., Hruban, R.H., Kern, S.E. Science (1996) [Pubmed]
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  9. BRCA1 is secreted and exhibits properties of a granin. Jensen, R.A., Thompson, M.E., Jetton, T.L., Szabo, C.I., van der Meer, R., Helou, B., Tronick, S.R., Page, D.L., King, M.C., Holt, J.T. Nat. Genet. (1996) [Pubmed]
  10. Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease. Nelen, M.R., van Staveren, W.C., Peeters, E.A., Hassel, M.B., Gorlin, R.J., Hamm, H., Lindboe, C.F., Fryns, J.P., Sijmons, R.H., Woods, D.G., Mariman, E.C., Padberg, G.W., Kremer, H. Hum. Mol. Genet. (1997) [Pubmed]
  11. Transduction of wild-type merlin into human schwannoma cells decreases schwannoma cell growth and induces apoptosis. Schulze, K.M., Hanemann, C.O., Müller, H.W., Hanenberg, H. Hum. Mol. Genet. (2002) [Pubmed]
  12. Constitutive expression of the Wilms tumor suppressor gene WT1 in F9 embryonal carcinoma cells induces apoptotic cell death in response to retinoic acid. Kudoh, T., Ishidate, T., Nakamura, T., Toyoshima, K., Akiyama, T. Oncogene (1996) [Pubmed]
  13. Expression of the baculovirus p35 gene inhibits mammalian neural cell death. Rabizadeh, S., LaCount, D.J., Friesen, P.D., Bredesen, D.E. J. Neurochem. (1993) [Pubmed]
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  16. Germline intronic and exonic mutations in the Wilms' tumour gene (WT1) affecting urogenital development. Bruening, W., Bardeesy, N., Silverman, B.L., Cohn, R.A., Machin, G.A., Aronson, A.J., Housman, D., Pelletier, J. Nat. Genet. (1992) [Pubmed]
  17. Epigenetic lesions at the H19 locus in Wilms' tumour patients. Moulton, T., Crenshaw, T., Hao, Y., Moosikasuwan, J., Lin, N., Dembitzer, F., Hensle, T., Weiss, L., McMorrow, L., Loew, T. Nat. Genet. (1994) [Pubmed]
  18. 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. Chan, T.A., Hermeking, H., Lengauer, C., Kinzler, K.W., Vogelstein, B. Nature (1999) [Pubmed]
  19. 5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Merlo, A., Herman, J.G., Mao, L., Lee, D.J., Gabrielson, E., Burger, P.C., Baylin, S.B., Sidransky, D. Nat. Med. (1995) [Pubmed]
  20. Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL. Hergovich, A., Lisztwan, J., Barry, R., Ballschmieter, P., Krek, W. Nat. Cell Biol. (2003) [Pubmed]
  21. Comparative analysis and genomic structure of the tuberous sclerosis 2 (TSC2) gene in human and pufferfish. Maheshwar, M.M., Sandford, R., Nellist, M., Cheadle, J.P., Sgotto, B., Vaudin, M., Sampson, J.R. Hum. Mol. Genet. (1996) [Pubmed]
  22. Isolation and characterization of an apoptosis-resistant variant of human leukemia HL-60 cells that has switched expression from Bcl-2 to Bcl-xL. Han, Z., Chatterjee, D., Early, J., Pantazis, P., Hendrickson, E.A., Wyche, J.H. Cancer Res. (1996) [Pubmed]
  23. von Hippel-Lindau gene-mediated growth suppression and induction of differentiation in renal cell carcinoma cells grown as multicellular tumor spheroids. Lieubeau-Teillet, B., Rak, J., Jothy, S., Iliopoulos, O., Kaelin, W., Kerbel, R.S. Cancer Res. (1998) [Pubmed]
  24. A functional polymorphism in the prodynorphin gene promotor is associated with temporal lobe epilepsy. Stögmann, E., Zimprich, A., Baumgartner, C., Aull-Watschinger, S., Höllt, V., Zimprich, F. Ann. Neurol. (2002) [Pubmed]
  25. Mutations at a Zn(II) finger motif in the yeast eIF-2 beta gene alter ribosomal start-site selection during the scanning process. Donahue, T.F., Cigan, A.M., Pabich, E.K., Valavicius, B.C. Cell (1988) [Pubmed]
  26. Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation. Marsh, D.J., Coulon, V., Lunetta, K.L., Rocca-Serra, P., Dahia, P.L., Zheng, Z., Liaw, D., Caron, S., Duboué, B., Lin, A.Y., Richardson, A.L., Bonnetblanc, J.M., Bressieux, J.M., Cabarrot-Moreau, A., Chompret, A., Demange, L., Eeles, R.A., Yahanda, A.M., Fearon, E.R., Fricker, J.P., Gorlin, R.J., Hodgson, S.V., Huson, S., Lacombe, D., Eng, C. Hum. Mol. Genet. (1998) [Pubmed]
  27. Establishment of a system for conditional gene expression using an inducible tRNA suppressor gene. Dingermann, T., Werner, H., Schütz, A., Zündorf, I., Nerke, K., Knecht, D., Marschalek, R. Mol. Cell. Biol. (1992) [Pubmed]
  28. The staurosporine analog, Ro-31-8220, induces apoptosis independently of its ability to inhibit protein kinase C. Han, Z., Pantazis, P., Lange, T.S., Wyche, J.H., Hendrickson, E.A. Cell Death Differ. (2000) [Pubmed]
  29. Mode of mutagenic action of methylnitrosocyanamide, a potent carcinogen. Hidaka, K., Ishizawa, M., Otsuji, N., Endo, H. Cancer Res. (1978) [Pubmed]
  30. Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation. Garkavtsev, I., Kazarov, A., Gudkov, A., Riabowol, K. Nat. Genet. (1996) [Pubmed]
  31. SSL2, a suppressor of a stem-loop mutation in the HIS4 leader encodes the yeast homolog of human ERCC-3. Gulyas, K.D., Donahue, T.F. Cell (1992) [Pubmed]
  32. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Rhee, I., Bachman, K.E., Park, B.H., Jair, K.W., Yen, R.W., Schuebel, K.E., Cui, H., Feinberg, A.P., Lengauer, C., Kinzler, K.W., Baylin, S.B., Vogelstein, B. Nature (2002) [Pubmed]
  33. The yeast tRNATyr gene intron is essential for correct modification of its tRNA product. Johnson, P.F., Abelson, J. Nature (1983) [Pubmed]
  34. Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae. Kadaba, S., Krueger, A., Trice, T., Krecic, A.M., Hinnebusch, A.G., Anderson, J. Genes Dev. (2004) [Pubmed]
  35. Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation. Davies, J.A., Ladomery, M., Hohenstein, P., Michael, L., Shafe, A., Spraggon, L., Hastie, N. Hum. Mol. Genet. (2004) [Pubmed]
  36. The p53 tumour suppressor gene: a model for molecular epidemiology of human cancer. Soussi, T. Molecular medicine today. (1996) [Pubmed]
  37. Angiogenic factor VEGF is decreased in human colorectal neoplasms showing DNA microsatellite instability. Wynter, C.V., Simms, L.A., Buttenshaw, R.L., Biden, K.G., Young, J., Leggett, B.A., Conrad, R.J., Schoch, E.M., Jass, J.R., Praga Pillay, S. J. Pathol. (1999) [Pubmed]
  38. Increased expression of the NME1 gene is associated with metastasis in epithelial ovarian cancer. Leary, J.A., Kerr, J., Chenevix-Trench, G., Doris, C.P., Hurst, T., Houghton, C.R., Friedlander, M.L. Int. J. Cancer (1995) [Pubmed]
  39. Polymerase chain reaction in the assessment of lymphomas. Diss, T.C., Pan, L. Cancer Surv. (1997) [Pubmed]
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