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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

HNT1  -  Hnt1p

Saccharomyces cerevisiae S288c

Synonyms: Adenosine 5'-monophosphoramidase, HIT1, Hit family protein 1, YDL125C
 
 
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High impact information on HNT1

  • The target of Hnt1 regulation in this pathway was shown to be downstream of Cak1 and not to affect stability of Kin28 monomers [1].
  • Yeast strains constructed with specific loss of the Hnt1 active site fail to grow on galactose at elevated temperatures [1].
  • Functional complementation of all Hnt1 phenotypes was provided by rabbit Hint, which is only 22% identical to yeast Hnt1 but has very similar adenosine monophosphoramidase activity [1].

References

  1. Adenosine monophosphoramidase activity of Hint and Hnt1 supports function of Kin28, Ccl1, and Tfb3. Bieganowski, P., Garrison, P.N., Hodawadekar, S.C., Faye, G., Barnes, L.D., Brenner, C. J. Biol. Chem. (2002) [Pubmed]
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