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Gene Review

MET32  -  Met32p

Saccharomyces cerevisiae S288c

Synonyms: Methionine-requiring protein 32, Transcriptional regulator MET32, YD9320A.03C, YDR253C
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High impact information on MET32

  • Both LexA-Met31p and LexA-Met32p fusion proteins activate the transcription of a LexAop-containing promoter in a Met4p-dependent manner [1].
  • Northern blot analyses of cells that do not express either Met31p and/or Met32p suggest that the function of the two proteins during the transcriptional regulation of the sulfur network varies from one gene to the other [1].
  • Met31p was isolated through the use of the one-hybrid method, while Met32p was identified during the analysis of the yeast methionine transport system [1].

Biological context of MET32

  • Met31p and Met32p, two related zinc finger proteins, are involved in transcriptional regulation of yeast sulfur amino acid metabolism [1].

Other interactions of MET32

  • The Met4, Met31, and Met32 transcription factors may play a role in coregulating genes involved in copper and iron metabolism [2].


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