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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

SEF1  -  Sef1p

Saccharomyces cerevisiae S288c

Synonyms: Suppressor of essential function protein 1, Suppressor protein SEF1, YBL0501, YBL0526, YBL066C
 
 
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High impact information on SEF1

  • The SEF1 homologue of S. cerevisiae also compensates for the essential function of RPM2 [1].
  • We have named this gene SEF1 (Suppressor of the Essential Function), DNA sequence analysis of SEF1 reveals it contains a Zn(2)-Cys(6) binuclear cluster motif found in a growing number of yeast transcription factors [1].
  • YBL0515 and YBL0526 ORFs seem to be involved in the sporulation process [2].
  • Partial DNA sequencing of tagged genes showed that they were homologous to the S. cerevisiae genes RIB1, MET2, and SEF1 [3].

References

  1. Kluyveromyces lactis SEF1 and its Saccharomyces cerevisiae homologue bypass the unknown essential function, but not the mitochondrial RNase P function, of the S. cerevisiae RPM2 gene. Groom, K.R., Heyman, H.C., Steffen, M.C., Hawkins, L., Martin, N.C. Yeast (1998) [Pubmed]
  2. Sequencing and functional analysis of a 32,560 bp segment on the left arm of yeast chromosome II. Identification of 26 open reading frames, including the KIP1 and SEC17 genes. Scherens, B., el Bakkoury, M., Vierendeels, F., Dubois, E., Messenguy, F. Yeast (1993) [Pubmed]
  3. Insertion mutagenesis of the yeast Candida famata (Debaryomyces hansenii) by random integration of linear DNA fragments. Dmytruk, K.V., Voronovsky, A.Y., Sibirny, A.A. Curr. Genet. (2006) [Pubmed]
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