The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

PCL10  -  Pcl10p

Saccharomyces cerevisiae S288c

Synonyms: G2838, PHO85 cyclin-10, YGL134W
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of PCL10

 

High impact information on PCL10

  • We suggest a model for Pho85p function in the cell whereby cyclins like Pcl10p recruit Pho85p from a pool of monomers, both activating the kinase and targeting it to substrate [1].
  • Gsy2p phosphorylation required Pcl10p, occurred at physiologically relevant sites, and resulted in inactivation of Gsy2p [1].
  • Pcl10p is one of four Pcls with little sequence similarity to cyclins involved in cell cycle control [1].
  • In contrast, deletion of PCL8 and PCL10 in the coq3 mutant background partially restores glycogen accumulation [2].
 

Associations of PCL10 with chemical compounds

 

Other interactions of PCL10

  • In conjunction with Pcl8p and Pcl10p, Pho85p phosphorylates and regulates glycogen synthase [2].
 

Analytical, diagnostic and therapeutic context of PCL10

  • Gel filtration of yeast cell lysates demonstrated that most Pho85p was present as a monomer, although a portion coeluted in high-molecular-weight fractions with Pcl10p and Gsy2p [1].

References

 
WikiGenes - Universities