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Gene Review

SPG1  -  Spg1p

Saccharomyces cerevisiae S288c

Synonyms: G8578, Stationary phase gene 1 protein, YGR236C
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High impact information on SPG1

  • Byr4 inhibited the dissociation and hydrolysis of GTP bound to Spg1, but when Byr4 and Cdc16 were combined together they displayed Spg1GAP activity in vitro; Cdc16 alone had no detectable GAP activity [1].
  • The results suggest that the spg1 suppressor mutations allow S. cerevisiae pgil delta mutant strains to grow on glucose by using the Pentose-P cycle in combination with unusual strong respiration [2].

Analytical, diagnostic and therapeutic context of SPG1


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