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Gene Review

CTK2  -  Ctk2p

Saccharomyces cerevisiae S288c

Synonyms: CTD kinase 38 kDa subunit, CTD kinase subunit 2, CTD kinase subunit beta, CTDK-I subunit beta, J1390, ...
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High impact information on CTK2

  • Ctk1 is a Saccharomyces cerevisiae cyclin-dependent protein kinase (CDK) that assembles with Ctk2 and Ctk3 to form an active protein kinase complex, CTDK-I [1].
  • Strikingly, neither phosphorylation nor destruction of Ctk2p requires its associated kinase Ctk1p, a feature fundamentally different from that which has been observed for cell cycle cyclins [2].
  • Surprisingly, unlike what has been described for cell cycle cyclins, steady-state levels of Ctk2p are composed of two relatively abundant forms, one of them phosphorylated [2].

Biological context of CTK2


Other interactions of CTK2

  • The CTK2 gene encodes a cyclin-related protein with limited homology to cyclin C, while CTK3 shows no similarity to other known proteins [4].


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