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Gene Review

SET3  -  Set3p

Saccharomyces cerevisiae S288c

Synonyms: SET domain-containing protein 3, YKR029C
 
 
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High impact information on SET3

  • The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program [1].
  • Deletion of HOS2 or SET3 reduced the mobility of a chromosomal Ty1his3AI element about sevenfold [2].

References

  1. The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program. Pijnappel, W.W., Schaft, D., Roguev, A., Shevchenko, A., Tekotte, H., Wilm, M., Rigaut, G., Séraphin, B., Aasland, R., Stewart, A.F. Genes Dev. (2001) [Pubmed]
  2. Hos2 and Set3 Promote Integration of Ty1 Retrotransposons at tRNA Genes in Saccharomyces cerevisiae. Mou, Z., Kenny, A.E., Curcio, M.J. Genetics (2006) [Pubmed]
 
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