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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

YTM1  -  Ytm1p

Saccharomyces cerevisiae S288c

Synonyms: Microtubule-associated protein YTM1, Ribosome biogenesis protein YTM1, YOR272W
 
 
 
 
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High impact information on YTM1

  • Mutations in the WD40 motifs of Ytm1 disrupt binding to Erb1, destabilize the heterotrimer, and delay pre-rRNA processing and nuclear export of preribosomes [1].
  • Ytm1 is present in four consecutive 66S preribosomes containing 27SA2, 27SA3, 27SB, and 25.5S plus 7S pre-rRNAs plus ribosome assembly factors and ribosomal proteins [1].

References

  1. Ytm1, Nop7, and Erb1 form a complex necessary for maturation of yeast 66S preribosomes. Miles, T.D., Jakovljevic, J., Horsey, E.W., Harnpicharnchai, P., Tang, L., Woolford, J.L. Mol. Cell. Biol. (2005) [Pubmed]
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