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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

GIS4  -  Gis4p

Saccharomyces cerevisiae S288c

Synonyms: Protein GIS4, YM9571.13C, YML006C
 
 
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High impact information on GIS4

  • SCFGrr1-mediated ubiquitination of Gis4 modulates glucose response in yeast [1].
  • GIS3 and GIS4 predict proteins with no obvious similarities to any known proteins [2].
  • Genetic evidence suggests that Gis4 mediates its function in salt tolerance, at least partly, together with the Snf1 protein kinase and in parallel with the calcineurin protein phosphatase [3].
  • Gis4, a New Component of the Ion Homeostasis System in the Yeast Saccharomyces cerevisiae [3].
  • Gis4 is enriched at the cell surface, probably due to C-terminal farnesylation [3].

References

  1. SCFGrr1-mediated ubiquitination of Gis4 modulates glucose response in yeast. La Rue, J., Tokarz, S., Lanker, S. J. Mol. Biol. (2005) [Pubmed]
  2. Yeast genes GIS1-4: multicopy suppressors of the Gal- phenotype of snf1 mig1 srb8/10/11 cells. Balciunas, D., Ronne, H. Mol. Gen. Genet. (1999) [Pubmed]
  3. Gis4, a New Component of the Ion Homeostasis System in the Yeast Saccharomyces cerevisiae. Ye, T., Garc??a-Salcedo, R., Ramos, J., Hohmann, S. Eukaryotic Cell (2006) [Pubmed]
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