The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

CDC14B  -  cell division cycle 14B

Homo sapiens

Synonyms: CDC14 cell division cycle 14 homolog B, CDC14B3, Cdc14B1, Cdc14B2, Dual specificity protein phosphatase CDC14B, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on CDC14B


Biological context of CDC14B

  • A CDC14B mutant defective in catalyzing dephosphorylation fails to change the phosphorylation status or abundance of SIRT2 protein [2].
  • Overexpression of the human CDC14A and CDC14B genes complemented, although very poorly, S. cerevisiae cdc15-lyt1 and dbf2-2 mutants, suggesting a conserved function of these genes throughout phylogeny [4].


  1. The dual-specificity phosphatase CDC14B bundles and stabilizes microtubules. Cho, H.P., Liu, Y., Gomez, M., Dunlap, J., Tyers, M., Wang, Y. Mol. Cell. Biol. (2005) [Pubmed]
  2. Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle. Dryden, S.C., Nahhas, F.A., Nowak, J.E., Goustin, A.S., Tainsky, M.A. Mol. Cell. Biol. (2003) [Pubmed]
  3. The elusive multiple self-healing squamous epithelioma (MSSE) gene: further mapping, analysis of candidates, and loss of heterozygosity. Bose, S., Morgan, L.J., Booth, D.R., Goudie, D.R., Ferguson-Smith, M.A., Richards, F.M. Oncogene (2006) [Pubmed]
  4. A single-copy suppressor of the Saccharomyces cerevisae late-mitotic mutants cdc15 and dbf2 is encoded by the Candida albicans CDC14 gene. Jiménez, J., Cid, V.J., Nombela, C., Sánchez, M. Yeast (2001) [Pubmed]
WikiGenes - Universities