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Gene Review

MSSE  -  multiple self-healing squamous epithelioma

Homo sapiens

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Disease relevance of MSSE


Psychiatry related information on MSSE

  • OBJECTIVE: to study possible interrelations existing between the Mini-Suffering State Examination (MSSE) scale and survival of end-stage dementia patients [6].
  • CONCLUSIONS: We conclude that MSSE is appropriate for assessing self-efficacy in the MS population [7].
  • The MS Self-Efficacy Scale (MSSE), Rosenberg Self-Esteem Scale, Herth Hope Index, and Performance Scales; a sociodemographic questionnaire; and an information sheet regarding consent to participate in the study were mailed to 1,200 potential participants [8].

High impact information on MSSE


Chemical compound and disease context of MSSE


Biological context of MSSE


Anatomical context of MSSE


Associations of MSSE with chemical compounds

  • For 10 of the clinical isolates (two MSSA, three MRSA, two MSSE, three MRSE) and the reference strain, the interaction of cefepime and vancomycin was also determined by the time-kill method [12].
  • Minimum inhibitory concentrations (MIC90) and geometric mean MICs for sparfloxacin were as follows (mg/l): P. aeruginosa 128-23.7, E. cloacae 1-0.13, A. anitratus 2-0.14, K. pneumoniae 1-0.08, MRSA 16-0.98, MSSA 0.12-0.03, MRSE 0.25-0.12 and MSSE 0.12-0.05 [16].
  • We also present a novel method, termed methylation-specific strand extension (MSSE), for the detection of methylated CpG dinucleotides [13].
  • RESULTS: The MSSE has high internal consistency and test-retest reliability, both for the overall scale and for the SE Function and SE Control subscales [7].
  • The MSSE measured at the initiation of glatiramer acetate therapy correctly classified 98.8% of those who were adherent at the 6-month follow-up [17].

Other interactions of MSSE


Analytical, diagnostic and therapeutic context of MSSE


  1. Mapping the multiple self-healing squamous epithelioma (MSSE) gene and investigation of xeroderma pigmentosum group A (XPA) and PATCHED (PTCH) as candidate genes. Richards, F.M., Goudie, D.R., Cooper, W.N., Jene, Q., Barroso, I., Wicking, C., Wainwright, B.J., Ferguson-Smith, M.A. Hum. Genet. (1997) [Pubmed]
  2. In-vitro and in-vivo antibacterial activity of LB10517, a novel catechol-substituted cephalosporin with a broad antibacterial spectrum. Song, H.K., Oh, J.I., Kim, M.Y., Kim, Y.Z., Kim, I.C., Kwak, J.H. J. Antimicrob. Chemother. (1996) [Pubmed]
  3. In vitro activity of quinupristin/dalfopristin against clinical isolates of common gram-positive bacteria in Taiwan. Chang, S.C., Fang, C.T., Hsueh, P.R., Luh, K.T., Hsieh, W.C. Diagn. Microbiol. Infect. Dis. (1999) [Pubmed]
  4. Differential allele loss on chromosome 9q22.3 in human non-melanoma skin cancer. Holmberg, E., Rozell, B.L., Toftgård, R. Br. J. Cancer (1996) [Pubmed]
  5. Desmoglein in multiple self-healing squamous epithelioma of Ferguson-Smith--comparison of staining patterns with actinic keratoacanthoma and squamous cell carcinoma of the skin. Krunic, A.L., Garrod, D.R., Hunter, J.A., Clark, R.E. Arch. Dermatol. Res. (1998) [Pubmed]
  6. Their last 6 months: suffering and survival of end-stage dementia patients. Aminoff, B.Z., Adunsky, A. Age and ageing. (2006) [Pubmed]
  7. Measuring self-efficacy in people with multiple sclerosis: a validation study. Schwartz, C.E., Coulthard-Morris, L., Zeng, Q., Retzlaff, P. Archives of physical medicine and rehabilitation. (1996) [Pubmed]
  8. Predictors of adherence to glatiramer acetate therapy in individuals with self-reported progressive forms of multiple sclerosis. Fraser, C., Hadjimichael, O., Vollmer, T. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses. (2003) [Pubmed]
  9. Evidence for two tumor suppressor loci associated with proximal chromosome 9p to q and distal chromosome 9q in bladder cancer and the initial screening for GAS1 and PTC mutations. Simoneau, A.R., Spruck, C.H., Gonzalez-Zulueta, M., Gonzalgo, M.L., Chan, M.F., Tsai, Y.C., Dean, M., Steven, K., Horn, T., Jones, P.A. Cancer Res. (1996) [Pubmed]
  10. The elusive multiple self-healing squamous epithelioma (MSSE) gene: further mapping, analysis of candidates, and loss of heterozygosity. Bose, S., Morgan, L.J., Booth, D.R., Goudie, D.R., Ferguson-Smith, M.A., Richards, F.M. Oncogene (2006) [Pubmed]
  11. Four tumor suppressor loci on chromosome 9q in bladder cancer: evidence for two novel candidate regions at 9q22.3 and 9q31. Simoneau, M., Aboulkassim, T.O., LaRue, H., Rousseau, F., Fradet, Y. Oncogene (1999) [Pubmed]
  12. In vitro synergy between cefepime and vancomycin against methicillin-susceptible and -resistant Staphylococcus aureus and Staphylococcus epidermidis. Lozniewski, A., Lion, C., Mory, F., Weber, M. J. Antimicrob. Chemother. (2001) [Pubmed]
  13. Mutation and methylation analysis of the transforming growth factor beta receptor II gene in polycythaemia vera. Li, J., Bench, A.J., Huntly, B.J., Green, A.R. Br. J. Haematol. (2001) [Pubmed]
  14. A YAC-based transcript map of human chromosome 9q22.1-q22.3 encompassing the loci for hereditary sensory neuropathy type I and multiple self-healing squamous epithelioma. Blair, I.P., Hulme, D., Dawkins, J.L., Nicholson, G.A. Genomics (1998) [Pubmed]
  15. Evoked potential abnormalities in myotonic dystrophy. Thompson, D.S., Woodward, J.B., Ringel, S.P., Nelson, L.M. Electroencephalography and clinical neurophysiology. (1983) [Pubmed]
  16. Comparative in vitro activity of sparfloxacin (AT 4140, RP 64206--SPFX) against 275 multiresistant clinical isolates. Giamarellou, H., Voutsinas, D., Xirouchaki, E. Journal of chemotherapy (Florence, Italy) (1992) [Pubmed]
  17. A prospective study of adherence to glatiramer acetate in individuals with multiple sclerosis. Fraser, C., Morgante, L., Hadjimichael, O., Vollmer, T. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses. (2004) [Pubmed]
  18. Measuring the suffering of end-stage dementia: reliability and validity of the Mini-Suffering State Examination. Aminoff, B.Z., Purits, E., Noy, S., Adunsky, A. Archives of gerontology and geriatrics. (2004) [Pubmed]
  19. The "sins" of the fathers: self-healing squamous epithelioma in Scotland. Bale, S.J. Journal of cutaneous medicine and surgery. (1999) [Pubmed]
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