Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

GPI2 - Gpi2p

Saccharomyces cerevisiae S288c

Synonyms: GCR4, LPF9W, Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit, YPL076W

Leidich, S.D. et al., Uemura, H. et al.

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High impact information on GPI2

Temperature-sensitive yeast GPI anchoring mutants gpi2 and gpi3 are defective in the synthesis of N-acetylglucosaminyl phosphatidylinositol. Cloning of the GPI2 gene [1].
A new essential gene GCR4 located in the upstream region of GCR1 [2].

Biological context of GPI2

Haploid Saccharomyces cerevisiae strains containing any pairwise combination of the gpi1, gpi2, and gpi3 mutations are inviable [1].

References

Temperature-sensitive yeast GPI anchoring mutants gpi2 and gpi3 are defective in the synthesis of N-acetylglucosaminyl phosphatidylinositol. Cloning of the GPI2 gene. Leidich, S.D., Kostova, Z., Latek, R.R., Costello, L.C., Drapp, D.A., Gray, W., Fassler, J.S., Orlean, P. J. Biol. Chem. (1995) [Pubmed]
A new essential gene GCR4 located in the upstream region of GCR1. Uemura, H., Jigami, Y. Yeast (1995) [Pubmed]

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