Gene Review:
GCR1 - Gcr1p
Saccharomyces cerevisiae S288c
Synonyms:
Glycolytic genes transcriptional activator GCR1, LPF10, LPF10W, SIT3, YPL075W
- A simple in vivo footprinting method to examine DNA-protein interactions over the yeast PYK UAS element. Dumitru, I., McNeil, J.B. Nucleic Acids Res. (1994)
- GCR1, a transcriptional activator in Saccharomyces cerevisiae, complexes with RAP1 and can function without its DNA binding domain. Tornow, J., Zeng, X., Gao, W., Santangelo, G.M. EMBO J. (1993)
- Multiple domains of repressor activator protein 1 contribute to facilitated binding of glycolysis regulatory protein 1. López, M.C., Smerage, J.B., Baker, H.V. Proc. Natl. Acad. Sci. U.S.A. (1998)
- GCR1 of Saccharomyces cerevisiae encodes a DNA binding protein whose binding is abolished by mutations in the CTTCC sequence motif. Baker, H.V. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Activation mechanism of the multifunctional transcription factor repressor-activator protein 1 (Rap1p). Drazinic, C.M., Smerage, J.B., López, M.C., Baker, H.V. Mol. Cell. Biol. (1996)
- A complex regulatory element from the yeast gene ENO2 modulates GCR1-dependent transcriptional activation. Willett, C.E., Gelfman, C.M., Holland, M.J. Mol. Cell. Biol. (1993)
- Mutations in GCR1 affect SUC2 gene expression in Saccharomyces cerevisiae. Türkel, S., Turgut, T., López, M.C., Uemura, H., Baker, H.V. Mol. Genet. Genomics (2003)
- Characterization of the DNA-binding activity of GCR1: in vivo evidence for two GCR1-binding sites in the upstream activating sequence of TPI of Saccharomyces cerevisiae. Huie, M.A., Scott, E.W., Drazinic, C.M., Lopez, M.C., Hornstra, I.K., Yang, T.P., Baker, H.V. Mol. Cell. Biol. (1992)
- Concerted action of the transcriptional activators REB1, RAP1, and GCR1 in the high-level expression of the glycolytic gene TPI. Scott, E.W., Baker, H.V. Mol. Cell. Biol. (1993)
- A hexose transporter homologue controls glucose repression in the methylotrophic yeast Hansenula polymorpha. Stasyk, O.V., Stasyk, O.G., Komduur, J., Veenhuis, M., Cregg, J.M., Sibirny, A.A. J. Biol. Chem. (2004)
- The GCR1 requirement for yeast glycolytic gene expression is suppressed by dominant mutations in the SGC1 gene, which encodes a novel basic-helix-loop-helix protein. Nishi, K., Park, C.S., Pepper, A.E., Eichinger, G., Innis, M.A., Holland, M.J. Mol. Cell. Biol. (1995)
- Cell cycle arrest determines the intensity of the global transcriptional response of Saccharomyces cerevisiae to ionizing radiation. De Sanctis, V., Bertozzi, C., Costanzo, G., Di Mauro, E., Negri, R. Radiat. Res. (2001)
- gcr2, a new mutation affecting glycolytic gene expression in Saccharomyces cerevisiae. Uemura, H., Fraenkel, D.G. Mol. Cell. Biol. (1990)
- The yeast protein Gcr1p binds to the PGK UAS and contributes to the activation of transcription of the PGK gene. Henry, Y.A., López, M.C., Gibbs, J.M., Chambers, A., Kingsman, S.M., Baker, H.V., Stanway, C.A. Mol. Gen. Genet. (1994)
- The GCR2 gene is required for the transcriptional activation of retrotransposon Ty2-917 in Saccharomyces cerevisiae. Türkel, S. Biol. Pharm. Bull. (2002)
- Mutations in GCR1, a transcriptional activator of Saccharomyces cerevisiae glycolytic genes, function as suppressors of gcr2 mutations. Uemura, H., Jigami, Y. Genetics (1995)
- Transcription of the HXT4 gene is regulated by Gcr1p and Gcr2p in the yeast S. cerevisiae. Türkel, S., Bisson, L.F. Yeast (1999)
- Role of GCR2 in transcriptional activation of yeast glycolytic genes. Uemura, H., Jigami, Y. Mol. Cell. Biol. (1992)
- The GCR1 gene encodes a positive transcriptional regulator of the enolase and glyceraldehyde-3-phosphate dehydrogenase gene families in Saccharomyces cerevisiae. Holland, M.J., Yokoi, T., Holland, J.P., Myambo, K., Innis, M.A. Mol. Cell. Biol. (1987)
- Understanding the growth phenotype of the yeast gcr1 mutant in terms of global genomic expression patterns. López, M.C., Baker, H.V. J. Bacteriol. (2000)