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Gene Review

LSM5  -  RNA-binding protein LSM5

Saccharomyces cerevisiae S288c

Synonyms: U6 snRNA-associated Sm-like protein LSm5, YER146W
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High impact information on LSM5

  • Association of the Saccharomyces cerevisiae La homologue Lhp1p with pre-tRNAs was reduced approximately threefold on depletion of Lsm3p or Lsm5p [1].
  • Additionally, we show that the Sm-like protein Lsm5p, which as part of Lsm complexes participates in cytosolic and nuclear RNA processing and degradation pathways, is a multicopy suppressor of the synthetic lethality and of the specific depletion of box H/ACA small nucleolar RNAs from the srp40Delta shm2 ade3 strain [2].


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