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Gene Review

B4GALT4  -  UDP-Gal:betaGlcNAc beta 1,4-...

Homo sapiens

Synonyms: B4Gal-T4, Beta-1,4-GalTase 4, Beta-1,4-galactosyltransferase 4, Beta4Gal-T4, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4, ...
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High impact information on B4GALT4

  • All intron/exon boundaries were similarly positioned in beta4Gal-T1, -T2, and -T3. beta4Gal-T4 represents a new member of the beta4-galactosyltransferase family [1].
  • The genomic organization of the coding region of beta4Gal-T4 was contained in six exons [1].
  • The catalytic activity of beta4Gal-T4 with monosaccharide acceptor substrates, N-acetylglucosamine as well as glucose, was markedly activated in the presence of alpha-lactalbumin [1].
  • A novel putative member of the human UDP-galactose:beta-N-acetylglucosamine beta1,4-galactosyltransferase family, designated beta4Gal-T4, was identified by BLAST analysis of expressed sequence tags [1].


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