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Gene Review

pvdE  -  pyoverdine biosynthesis protein PvdE

Pseudomonas aeruginosa PAO1

 
 
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Disease relevance of pvdE

  • Characterisation of the pvdE gene which is required for pyoverdine synthesis in Pseudomonas aeruginosa [1].
 

High impact information on pvdE

  • Two divergent PvdS-dependent promoters (pvdE and pvdF) were characterized by deletion analysis, and the minimal promoter region for each included a sequence element, the iron starvation (IS) box, that is present in other pvd promoters [2].
  • The first mutant, which had an insertion in the pvdE gene, upstream of fpvA, was unable to take up type II PVD and showed resistance to pyocin S3, which is known to use type II FpvA as receptor [3].

References

  1. Characterisation of the pvdE gene which is required for pyoverdine synthesis in Pseudomonas aeruginosa. McMorran, B.J., Merriman, M.E., Rombel, I.T., Lamont, I.L. Gene (1996) [Pubmed]
  2. Analysis of promoters recognized by PvdS, an extracytoplasmic-function sigma factor protein from Pseudomonas aeruginosa. Wilson, M.J., McMorran, B.J., Lamont, I.L. J. Bacteriol. (2001) [Pubmed]
  3. Identification of type II and type III pyoverdine receptors from Pseudomonas aeruginosa. de Chial, M., Ghysels, B., Beatson, S.A., Geoffroy, V., Meyer, J.M., Pattery, T., Baysse, C., Chablain, P., Parsons, Y.N., Winstanley, C., Cordwell, S.J., Cornelis, P. Microbiology (Reading, Engl.) (2003) [Pubmed]
 
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