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Gene Review:

groEL - molecular chaperone GroEL

Pseudomonas aeruginosa PAO1

Finnan, S. et al., Fujita, M. et al., Hertveldt, K. et al.

Hertveldt, Lavigne, Pleteneva, Sernova, Kurochkina, Korchevskii, Robben, Mesyanzhinov, Krylov, Volckaert, Fujita, Amemura, Aramaki,

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Disease relevance of groEL

Northern hybridization and S1 nuclease mapping demonstrated that the groES and groEL genes in Pseudomonas aeruginosa were transcribed as a bicistronic mRNA of 2.2 kb [1].

High impact information on groEL

EL-gp146 is the first chaperonin GroEL sequence identified in a viral genome [2].
In this study, the evolutionary genetic relationships among 17 P. aeruginosa isolates were examined by comparative sequence analysis of the housekeeping gene encoding malate dehydrogenase and the chaperone groEL [3].

References

Transcription of the groESL operon in Pseudomonas aeruginosa PAO1. Fujita, M., Amemura, A., Aramaki, H. FEMS Microbiol. Lett. (1998) [Pubmed]
Genome comparison of Pseudomonas aeruginosa large phages. Hertveldt, K., Lavigne, R., Pleteneva, E., Sernova, N., Kurochkina, L., Korchevskii, R., Robben, J., Mesyanzhinov, V., Krylov, V.N., Volckaert, G. J. Mol. Biol. (2005) [Pubmed]
Genome diversity of Pseudomonas aeruginosa isolates from cystic fibrosis patients and the hospital environment. Finnan, S., Morrissey, J.P., O'Gara, F., Boyd, E.F. J. Clin. Microbiol. (2004) [Pubmed]

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