The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

SNORD73A  -  small nucleolar RNA, C/D box 73A

Homo sapiens

Synonyms: RNU73, RNU73A, U73, U73a
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of SNORD73A

  • The cysteine-tRNA synthetase of Escherichia coli has domains that select for tRNAs containing U73, the GCA anticodon, and a specific tertiary structure at the corner of the tRNA L shape [1].

High impact information on SNORD73A

  • We show here that, although the Escherichia coli and human cysteinyl-tRNA synthetases both recognize the same bases (U73 and the GCA anticodon) of tRNA for aminoacylation, they have different emphasis on the tRNA backbone [2].
  • We propose that U73 is involved in methylation of the G1739 residue of the human 28S rRNA [3].
  • In addition, we present the mapping of human ribosomal protein S3a gene (hRPS3a) and internally nested U73 gene to the human chromosome 4q31.2-3 [3].
  • A novel snoRNA (U73) is encoded within the introns of the human and mouse ribosomal protein S3a genes [3].


  1. Aminoacylation of tRNA in the evolution of an aminoacyl-tRNA synthetase. Lipman, R.S., Hou, Y.M. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  2. Recognition of tRNA backbone for aminoacylation with cysteine: evolution from Escherichia coli to human. Ming, X., Smith, K., Suga, H., Hou, Y.M. J. Mol. Biol. (2002) [Pubmed]
  3. A novel snoRNA (U73) is encoded within the introns of the human and mouse ribosomal protein S3a genes. Rebane, A., Tamme, R., Laan, M., Pata, I., Metspalu, A. Gene (1998) [Pubmed]
WikiGenes - Universities