The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

UBA3  -  ubiquitin-like modifier activating enzyme 3

Homo sapiens

Synonyms: NAE2, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1C, UBE1C, Ubiquitin-activating enzyme 3, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on UBE1C

  • We show that expression of APP-BP1 in ts41 cells drives the cell cycle through the S-M checkpoint and that this function requires both hUba3 and hUbc12 [1].
  • These data explain why the Ubc12-UBA3 interaction is unique to the NEDD8 pathway [2].

References

  1. The amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons. Chen, Y., McPhie, D.L., Hirschberg, J., Neve, R.L. J. Biol. Chem. (2000) [Pubmed]
  2. A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8. Huang, D.T., Miller, D.W., Mathew, R., Cassell, R., Holton, J.M., Roussel, M.F., Schulman, B.A. Nat. Struct. Mol. Biol. (2004) [Pubmed]
 
WikiGenes - Universities