Gene Review:
UBA3 - ubiquitin-like modifier activating enzyme 3
Homo sapiens
Synonyms:
NAE2, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1C, UBE1C, Ubiquitin-activating enzyme 3, ...
- The amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons. Chen, Y., McPhie, D.L., Hirschberg, J., Neve, R.L. J. Biol. Chem. (2000)
- A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8. Huang, D.T., Miller, D.W., Mathew, R., Cassell, R., Holton, J.M., Roussel, M.F., Schulman, B.A. Nat. Struct. Mol. Biol. (2004)