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Gene Review

TMEM257  -  transmembrane protein 257

Homo sapiens

Synonyms: CXorf1, Transmembrane protein 257
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High impact information on CXorf1

  • In particular, CXorf1 was localized in the granular-cell layer of the dentate gyrus and in the CA2-CA3 subfields of Ammon's horn [1].
  • In situ hybridization experiments performed on sections of human hippocampus showed a clear, uneven localization of the CXorf1 mRNA in specific subfields of this brain area [1].
  • We have identified and characterized a novel human gene (Nomenclature Committee of the Genome Database GDB-assigned symbol CXorf1) that maps to the long arm of the X chromosome in Xq27 between loci DXS369 and DXS181, approximately 2.5 Mb centromeric to the FMR1 gene [1].

Anatomical context of CXorf1


  1. Identification of CXorf1, a novel intronless gene in Xq27.3, expressed in human hippocampus. Redolfi, E., Montagna, C., Mumm, S., Affer, M., Susani, L., Reinbold, R., Hol, F., Vezzoni, P., Cimino, M., Zucchi, I. DNA Cell Biol. (1998) [Pubmed]
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