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Gene Review

ECs5013  -  phosphate-starvation-inducible protein PsiE

Escherichia coli O157:H7 str. Sakai

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Disease relevance of ECs5013

  • Members of this family are widespread among prokaryotes and include the products of a Salmonella enterica serovar Typhimurium gene expressed during invasion of macrophages and psiE, an Escherichia coli phosphate starvation-inducible gene [1].

High impact information on ECs5013

  • In addition, psiE-lacZ is negatively controlled by the cAMP and CAP system. psiO-lacZ is induced by phosphate-, carbon- or nitrogen-limited growth or by anaerobiosis [2].
  • Dual transcriptional regulation of the Escherichia coli phosphate-starvation-inducible psiE gene of the phosphate regulon by PhoB and the cyclic AMP (cAMP)-cAMP receptor protein complex [3].


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