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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

H1L  -  H1L

Monkeypox virus Zaire-96-I-16

 
 
 
 
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Disease relevance of H1L

  • To assess whether this is a common feature of poxvirus phosphatases, myxoma I1L was expressed as a GST-fusion protein, purified, and shown to dephosphorylate substrates containing tyrosine and serine phosphorylated residues, in a similar fashion to vaccinia H1L [1].

References

  1. Myxoma virus and Shope fibroma virus encode dual-specificity tyrosine/serine phosphatases which are essential for virus viability. Mossman, K., Ostergaard, H., Upton, C., McFadden, G. Virology (1995) [Pubmed]
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