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Gene Review

r144  -  pr144

Murid herpesvirus 2

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Disease relevance of r144


High impact information on r144

  • To study the role of r144 in virus replication, an RCMV r144 null mutant strain (RCMVDeltar144) was generated [1].
  • This suggests that r144 might function in the interaction with these leukocytes in vivo [1].
  • At 21 days p.i., RCMVdelta r144-infected rats were found to have lower virus titers in the salivary glands than wt RCMV-infected animals [2].

Biological context of r144

  • These data indicate that the RCMV r144 gene is essential neither for virus replication in the acute phase of infection nor for long-term infection in immunocompromised rats [1].


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