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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Major Histocompatibility Complex

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Disease relevance of Major Histocompatibility Complex


Psychiatry related information on Major Histocompatibility Complex


High impact information on Major Histocompatibility Complex


Chemical compound and disease context of Major Histocompatibility Complex


Biological context of Major Histocompatibility Complex


Anatomical context of Major Histocompatibility Complex


Associations of Major Histocompatibility Complex with chemical compounds


Gene context of Major Histocompatibility Complex


Analytical, diagnostic and therapeutic context of Major Histocompatibility Complex


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  2. A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis. Lincoln, M.R., Montpetit, A., Cader, M.Z., Saarela, J., Dyment, D.A., Tiislar, M., Ferretti, V., Tienari, P.J., Sadovnick, A.D., Peltonen, L., Ebers, G.C., Hudson, T.J. Nat. Genet. (2005) [Pubmed]
  3. Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands. Dick, T.P., Ruppert, T., Groettrup, M., Kloetzel, P.M., Kuehn, L., Koszinowski, U.H., Stevanović, S., Schild, H., Rammensee, H.G. Cell (1996) [Pubmed]
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  5. Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis. Schaible, U.E., Winau, F., Sieling, P.A., Fischer, K., Collins, H.L., Hagens, K., Modlin, R.L., Brinkmann, V., Kaufmann, S.H. Nat. Med. (2003) [Pubmed]
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  18. Specific tolerance to an acetylcholine receptor epitope induced in vitro in myasthenia gravis CD4+ lymphocytes by soluble major histocompatibility complex class II-peptide complexes. Nicolle, M.W., Nag, B., Sharma, S.D., Willcox, N., Vincent, A., Ferguson, D.J., Newsom-Davis, J. J. Clin. Invest. (1994) [Pubmed]
  19. Individuals with IgA deficiency and common variable immunodeficiency share polymorphisms of major histocompatibility complex class III genes. Schaffer, F.M., Palermos, J., Zhu, Z.B., Barger, B.O., Cooper, M.D., Volanakis, J.E. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
  20. Negative regulation of the major histocompatibility class I gene in undifferentiated embryonal carcinoma cells. Miyazaki, J., Appella, E., Ozato, K. Proc. Natl. Acad. Sci. U.S.A. (1986) [Pubmed]
  21. Antigen presentation by major histocompatibility complex class I-B molecules. Shawar, S.M., Vyas, J.M., Rodgers, J.R., Rich, R.R. Annu. Rev. Immunol. (1994) [Pubmed]
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  23. Expression of class I genes in the major histocompatibility complex: identification of eight distinct mRNAs in DBA/2 mouse liver. Lalanne, J.L., Transy, C., Guerin, S., Darche, S., Meulien, P., Kourilsky, P. Cell (1985) [Pubmed]
  24. Genetic prediction of nonresponse to hepatitis B vaccine. Alper, C.A., Kruskall, M.S., Marcus-Bagley, D., Craven, D.E., Katz, A.J., Brink, S.J., Dienstag, J.L., Awdeh, Z., Yunis, E.J. N. Engl. J. Med. (1989) [Pubmed]
  25. A pseudogene homologous to mouse transplantation antigens: transplantation antigens are encoded by eight exons that correlate with protein domains. Steinmetz, M., Moore, K.W., Frelinger, J.G., Sher, B.T., Shen, F.W., Boyse, E.A., Hood, L. Cell (1981) [Pubmed]
  26. T-lymphocyte recognition of antigen in association with gene products of the major histocompatibility complex. Schwartz, R.H. Annu. Rev. Immunol. (1985) [Pubmed]
  27. B-lymphocyte alloantigens associated with systemic lupus erythematosus. Reinertsen, J.L., Klippel, J.H., Johnson, A.H., Steinberg, A.D., Decker, J.L., Mann, D.L. N. Engl. J. Med. (1978) [Pubmed]
  28. A viral inhibitor of peptide transporters for antigen presentation. Früh, K., Ahn, K., Djaballah, H., Sempé, P., van Endert, P.M., Tampé, R., Peterson, P.A., Yang, Y. Nature (1995) [Pubmed]
  29. Influence of the major histocompatibility complex on lymphocyte interactions in antibody formation. Waldmann, H., Pope, H., Brent, L., Bighouse, K. Nature (1978) [Pubmed]
  30. The chondroitin sulfate form of invariant chain can enhance stimulation of T cell responses through interaction with CD44. Naujokas, M.F., Morin, M., Anderson, M.S., Peterson, M., Miller, J. Cell (1993) [Pubmed]
  31. Cell-specific expression of the human complement protein factor B gene: evidence for the role of two distinct 5'-flanking elements. Wu, L.C., Morley, B.J., Campbell, R.D. Cell (1987) [Pubmed]
  32. A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B. Carroll, M.C., Campbell, R.D., Bentley, D.R., Porter, R.R. Nature (1984) [Pubmed]
  33. Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck. Abraham, N., Miceli, M.C., Parnes, J.R., Veillette, A. Nature (1991) [Pubmed]
  34. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Youssef, S., Stüve, O., Patarroyo, J.C., Ruiz, P.J., Radosevich, J.L., Hur, E.M., Bravo, M., Mitchell, D.J., Sobel, R.A., Steinman, L., Zamvil, S.S. Nature (2002) [Pubmed]
  35. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Braud, V.M., Allan, D.S., O'Callaghan, C.A., Söderström, K., D'Andrea, A., Ogg, G.S., Lazetic, S., Young, N.T., Bell, J.I., Phillips, J.H., Lanier, L.L., McMichael, A.J. Nature (1998) [Pubmed]
  36. Class I-like HLA genes map telomeric to the HLA-A2 locus in human cells. Orr, H.T., DeMars, R. Nature (1983) [Pubmed]
  37. Evolution of the MHC class I genes of a New World primate from ancestral homologues of human non-classical genes. Watkins, D.I., Chen, Z.W., Hughes, A.L., Evans, M.G., Tedder, T.F., Letvin, N.L. Nature (1990) [Pubmed]
  38. Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1. Ohara, J., Paul, W.E. Nature (1985) [Pubmed]
  39. Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex. Kelly, A., Powis, S.H., Kerr, L.A., Mockridge, I., Elliott, T., Bastin, J., Uchanska-Ziegler, B., Ziegler, A., Trowsdale, J., Townsend, A. Nature (1992) [Pubmed]
  40. Primary structural: analysis of the transplantation antigens of the murine H-2 major histocompatibility complex. Nathenson, S.G., Uehara, H., Ewenstein, B.M., Kindt, T.J., Coligan, J.E. Annu. Rev. Biochem. (1981) [Pubmed]
  41. Capacity of purified Lyt-2+ T cells to mount primary proliferative and cytotoxic responses to Ia- tumour cells. Sprent, J., Schaefer, M. Nature (1986) [Pubmed]
  42. Mouse Ia antigens are receptors for lactate dehydrogenase virus. Inada, T., Mims, C.A. Nature (1984) [Pubmed]
  43. GM-CSF and TNF-alpha cooperate in the generation of dendritic Langerhans cells. Caux, C., Dezutter-Dambuyant, C., Schmitt, D., Banchereau, J. Nature (1992) [Pubmed]
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