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Gene Review:

napG - ferredoxin-type protein

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK2197, JW2193, yojA, yojB

Brondijk, T.H. et al.

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Disease relevance of napG

In Escherichia coli there are three additional genes, napF, napG and napH, none of which are essential for Nap activity [1].

High impact information on napG

We now show that deletion of either napG or napH almost abolished Nap-dependent nitrate reduction by strains defective in naphthoquinone synthesis [1].
The residual rate of nitrate reduction (approx. 1% of that of napG+ H+ strains) is sufficient to replace fumarate reduction in a redox-balancing role during growth by glucose fermentation [1].

References

NapGH components of the periplasmic nitrate reductase of Escherichia coli K-12: location, topology and physiological roles in quinol oxidation and redox balancing. Brondijk, T.H., Nilavongse, A., Filenko, N., Richardson, D.J., Cole, J.A. Biochem. J. (2004) [Pubmed]

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