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Gene Review

napF  -  ferredoxin-type protein, role in electron...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK2200, JW2196, yojG
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High impact information on napF

  • Utilizing a napF-lacZ operon fusion, we demonstrate that napF gene expression is impaired in strain defective for the molybdate-responsive ModE transcription factor [1].
  • The upstream ModE regulatory site functions to override nitrate control of napF gene expression when the essential enzyme component, molybdate, is limiting in the cell environment [1].
  • The nap operon encoding this nitrate reductase comprises seven genes including a gene, napF, that encodes a putative cytoplasmic iron-sulphur protein of uncertain subcellular location and function [2].

Associations of napF with chemical compounds

  • These findings indicate the involvement of an additional transcription factor to help coordinate nitrate- and molybdate-dependent napF expression by the Fnr, NarP, NarL, and ModE proteins [1].


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