Gene Review:
nfrB - bacteriophage N4 receptor, inner membrane...
Escherichia coli str. K-12 substr. MG1655
Synonyms:
ECK0561, JW0558
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Disease relevance of nfrB
- We propose that nfrA encodes the structural receptor for N4 and that the nfrB gene product may be required for irreversible adsorption and injection of the phage genome and virion-encapsulated RNA polymerase through the inner membrane [1].
- We mapped the mutations to four loci designated nfrA through nfrD (N four resistance). nfrA and nfrB were tightly linked to each other and were mapped to min 12 of the E. coli linkage map. nfrC was mapped to min 85, and nfrD was mapped between min 44 and 58 [1].
High impact information on nfrB
- We isolated a clone carrying both nfrA and nfrB and identified its gene products through maxicell analysis of plasmid subclones [1].
References
- Genetic analysis of bacteriophage N4 adsorption. Kiino, D.R., Rothman-Denes, L.B. J. Bacteriol. (1989) [Pubmed]
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