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Gene Review:

eamA - cysteine and O-acetyl-L-serine efflux system

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK1526, JW5250, ydeD

Franke, I. et al.

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High impact information on eamA

Since a ydeD-yfiK double mutant showed the same pattern, it appears that YfiK and YdeD act independently [1].
A DeltayfiK mutant did not show any phenotype, and it exported O-acetylserine and cysteine when transformed with a plasmid carrying ydeD, a previously characterized, alternate O-acetylserine/cysteine exporter [1].

Associations of eamA with chemical compounds

Overexpression of either ydeD or yfiK leads to alleviation of this inhibition paralled by increased resistance to azaserine, which is an analog of O-acetylserine [1].

References

YfiK from Escherichia coli promotes export of O-acetylserine and cysteine. Franke, I., Resch, A., Dassler, T., Maier, T., Böck, A. J. Bacteriol. (2003) [Pubmed]

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